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Tesamorelin-10mg (5mL Vial)
$187.50
Tesamorelin is a synthetic analogue of human growth hormone-releasing hormone (GHRH), specifically a modified version of the naturally occurring GHRH peptide. It consists of 44 amino acids and has been engineered to provide enhanced stability and a prolonged half-life in the body compared to endogenous GHRH. This modification allows for more sustained and consistent stimulation of the pituitary gland’s somatotroph cells.
Description
Quick Facts
Tesamorelin-10mg (5mL Vial) is a high-purity, lyophilized synthetic peptide designed for advanced research purposes. As a growth hormone-releasing hormone (GHRH) analog, Tesamorelin consists of 44 amino acids with a modified N-terminus, enhancing its stability and efficacy compared to natural GHRH. This peptide is widely studied for its ability to stimulate endogenous growth hormone (GH) production, offering potential applications in metabolic, endocrine, and body composition research. Supplied as a lyophilized powder, it requires reconstitution with bacteriostatic water for in vitro laboratory use.
Key Features
- Purity: ≥99% (HPLC verified), ensuring reliable and consistent research outcomes.
- Unit Size: 10mg per 5mL vial, ideal for precise dosing in experimental settings.
- Form: Lyophilized powder, stable for long-term storage at -20°C or below.
- Molecular Formula: C211H366N72O67S1, with a molecular weight of 5135.89 g/mol.
- Applications: Suitable for studies on growth hormone secretion, fat metabolism, and lipodystrophy.
Mechanism of Action
Tesamorelin mimics natural GHRH by binding to receptors on the pituitary gland’s somatotroph cells, triggering a cascade that activates adenylate cyclase and increases cyclic AMP (cAMP) levels. This process stimulates the pulsatile release of GH, which elevates insulin-like growth factor-1 (IGF-1) levels. Unlike exogenous GH, Tesamorelin promotes natural, physiological GH production, preserving the body’s regulatory mechanisms. Its modified structure, featuring a trans-3-hexenoyl group, enhances binding affinity and resistance to enzymatic degradation, ensuring prolonged activity.
Research Applications
Tesamorelin is extensively investigated for its potential in:
- Lipodystrophy: Reducing visceral adipose tissue in models of abnormal fat distribution.
- Metabolic Health: Modulating lipid metabolism and improving body composition.
- Cognitive Function: Exploring effects on neural health and cognitive performance in aging models.
- Cardiovascular Research: Studying impacts on metabolic parameters and cardiovascular risk factors.
- Endocrine Studies: Investigating GH and IGF-1 regulation in various research models.
Storage and Handling
Store Tesamorelin-10mg at -20°C or below in a cool, dark environment to maintain stability. Reconstitute with 2mL bacteriostatic water for research use. This product is intended strictly for in vitro laboratory research and is not for human or animal consumption.
Why Choose Tesamorelin-10mg?
Tesamorelin-10mg (5mL Vial) offers researchers a potent, high-purity peptide for exploring growth hormone pathways and metabolic regulation. Its enhanced stability and targeted action make it a valuable tool for cutting-edge studies in endocrinology and body composition. Order now to advance your research with this premium GHRH analog.
⚠️ *Important Notice: All peptides are supplied in a powdered (lyophilized) form. They must be reconstituted before use.